The moderate Republicans already signed a contract that they wouldn't support the "Nuclear Option".
From the original document:
Future Nominations Part B:
Rules Changes. In light of the spirit and continuing commitments made in this agreement,
we commit to oppose the rules changes in the 109th Congress, which we understand to be any
amendment to or interpretation of the Rules of the Senate that would force a vote on a
judicial nomination by means other than unanimous consent or Rule XXII.
There are NO conditions on their vote against the Nuclear Option.
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